WebCryptolepis sanguinolenta a plant that is used by traditional healers in Central and West Africa to treat infectious diseases, amoebiasis, and fever, including malaria [51,69]. Three bioactive alkaloids were isolated from the root bark, exhibiting higher in vitro antiplasmodial activity than chloroquine. WebCryptolepine ( Fig. 5) and neocryptolepine ( Fig. 5) are indoquinoline derivatives isolated from the roots of Cryptolepis sanguinolenta. These compounds have cytotoxic activities against P388 and HL-60 cancer cell lines ( Table 5 ). These compounds have been shown to intercalate into DNA, hindering the catalytic activity of human topoisomerase II.
In vitro and in vivo growth inhibitory activities of cryptolepine ...
WebJan 1, 2007 · The alkaloid cryptolepine is thought to mediate the anti-inflammatory effects of the climbing shrub, Cryptolepis sanguinoleta. The underlying mechanism of action, … WebMar 3, 2005 · A series of analogues of cryptolepine (1) have been synthesized and evaluated for their in vitro antiplasmodial and cytotoxic properties. The IC 50 values of several … how to stop religion civ 6
Himalayan honey loaded iron oxide nanoparticles: synthesis ...
WebDec 1, 2024 · Methods: Himalayan honey loaded iron oxide nanoparticles (HHLIO-NPs) were synthesized and X-ray diffraction (XRD) and scanning electron microscope (SEM) analyses were performed for characterization. UV-VIS spectra … WebJan 1, 2024 · Cryptolepine content in roots of C. sanguinolenta in response to fertilizer treatments within four growth periods. The growth periods/plant ages are in months after transplanting (MAT), and CK, K, N, NPK, and P denote the treatments applied: Control, Potassium, Nitrogen, combined NPK, and Phosphorus, respectively. WebCryptolepine C16H12N2 - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for … how to stop reliving traumatic events