Cthrc1 cancer
WebNov 14, 2024 · The high expression was confirmed by detecting the relative RNA expression of CTHRC1 in paired breast cancer and nontumor samples. The CTHRC1 transcriptional … WebJul 19, 2024 · Abstract. Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated …
Cthrc1 cancer
Did you know?
WebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett's esophagus and esophageal adenocarcinoma. WebFeb 15, 2024 · In CRC, the deletion of SMAD4 in cancer cells resulted in a decrease in S100A8+ monocytes in the tumor microenvironment . Furthermore, the release of Collagen Triple Helix Repeat Containing 1 (CTHRC1) by CRC cells induced M2 polarization of TAMs through TGFβ signaling and further promoted hepatic metastasis in mouse models …
WebOct 22, 2024 · The association of CTHRC1 with tumor progression is demonstrated in various human cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, GIST and colorectal cancer (1-3).In a meta-analysis done by Wang et al., the results revealed correlation of CTHRC1 expression with TNM stage in gastric cancer, … WebCTHRC1 has a role in pancreatic cancer progression and metastasis by regulating migration and adhesion activities of cancer cells. PMID: 23222813; Data indicate that the upregulated expression of collagen triple helix repeat containing 1 (CTHRC1) in gastric carcinogenesis contributes to tumor cell invasion and metastasis.
WebJun 20, 2024 · CTHRC1 is a secretory glycoprotein that was discovered while differentially expressed genes were screened after severe arterial injury in rats. 6,7 Subsequently, researchers reported that CTHRC1 is … WebJ Cancer 2016; 7(15):2213-2220. doi:10.7150/jca.16539 This issue Cite. Review. Multidimensional Roles of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in Malignant Cancers . Neng Jiang 1*, …
WebOct 6, 2024 · Ke, Z. et al. Overexpression of collagen triple helix repeat containing 1 (CTHRC1) is associated with tumour aggressiveness and poor prognosis in human non …
WebJun 23, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) has been found to be upregulated in ESCC. However, its role in tumourigenesis and progression of ESCC … crypto pairs screenerWebApr 10, 2024 · The strong invasive and metastatic nature of non-small cell lung cancer (NSCLC) leads to poor prognosis. Collagen triple helix repeat containing 1 (CTHRC1) is involved in cell migration, motility and invasion. The object of this study is to investigate the involvement of CTHRC1 in NSCLC invasion and metastasis. A proteomic analysis was … crypto pamm accountWebOct 6, 2024 · In the current study, we comprehensively analyzed CTHRC1 in distinct human cancer subtypes for the first time and find more closely CTHRC1-associated cancer … cryptpad wikipediaWebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt … cryptpad tabelleWebMar 21, 2024 · Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial … crypto panic newsWebSep 28, 2024 · CTHRC1, collagen triple helix repeat containing-1; CAF, cancer-associated fibroblast; CM, conditioned media. CAFs promote EMT alterations in BC cells by secreting CTHRC1 EMT is a recognized biological process that plays a key role in tumor metastasis, and is characterized by the loss of epithelial markers (such as E-cadherin) … crypto pantsWebMar 1, 2024 · Metastasis is the main cause of gastric cancer (GC) related death and the underlying mechanisms still remain unclear. Collagen triple helix repeat containing 1 (CTHRC1) protein is known to be involved in tissue remodeling processes and closely associated with carcinogenesis and metastasis in solid tumors, but the functional role of … crypto pancakeswap