WebDec 31, 2014 · Morvan’s Syndrome, or Morvan’s fibrillary chorea (MFC), is a rare autoimmune disease named after nineteenth century French physician Augustin Marie … Morvan's syndrome is a rare, life-threatening autoimmune disease named after the nineteenth century French physician Augustin Marie Morvan. "La chorée fibrillaire" was first coined by Morvan in 1890 when describing patients with multiple, irregular contractions of the long muscles, cramping, weakness, pruritus, … See more In one of the few reported cases, the subject presented with muscle weakness and fatigue, muscle twitching, excessive sweating and salivation, small joint pain, itching and weight loss. The subject also developed … See more Differential diagnosis The symptoms of Morvan's Syndrome have been noted to bear a striking similarity to limbic encephalitis (LE). These include the CNS symptoms consisting of insomnia, hallucinations, and disorientation, as … See more Antibodies against voltage-gated potassium channels (VGKC), which are detectable in about 40% of patients with acquired neuromytonia, have been implicated in Morvan's pathophysiology. Raised serum levels of antibodies to VGKCs have been … See more In most of the reported cases, the treatment options were very similar. Plasmapheresis alone or in combination with steroids, sometimes also with thymectomy See more There are only about 14 reported cases of Morvan's syndrome in the English literature. With only a limited number of reported cases, the complete spectrum of the See more

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Morvan’s fibrillary chorea – CheckOrphan

WebJun 24, 2024 · Morvan syndrome is an autoimmune disorder characterized by the following: (1) central nervous system dysfunction, such as neuropsychiatric symptoms, insomnia, and myoclonus; (2) autonomic symptoms, such as diffuse sweating and arrhythmia; and (3) peripheral hyperactivity, such as myokymia or neuromyotonia [].Agrypnia excitata, which … WebMorvan's fibrillary chorea. Morvan's syndrome is a rare, life-threatening autoimmune disease named after the nineteenth century French physician Augustin Marie Morvan. "La chorée fibrillaire" was first coined by Morvan in 1890 when describing patients with multiple, irregular contractions of the long muscles, cramping, weakness, pruritus ... WebThe most effective treatment was plasma exchange which was tried in 55% of the patients, all of whom except one patient showed dramatic improvement, and when … 9龍城寨